A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.

Snake Effect: A Novel Haptic Illusion

Snake Effect: A Novel Haptic Illusion

We current a novel, movement-based haptic phantasm referred to as the “snake impact.” Unlike obvious movement or sensory saltation, the snake impact feels wavy and creepy as if the stomach of a slithering snake is making and breaking contact with the pores and skin. This phantasm is achieved by modulating the amplitudes of vibrotactile pulses …

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A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.

We use in situ Hi-C to probe the 3D structure of genomes, developing haploid and diploid maps of 9 cell sorts. The densest, in human lymphoblastoid cells, incorporates 4.9 billion contacts, reaching 1 kb resolution. We discover that genomes are partitioned into contact domains (median size, 185 kb), that are related to distinct patterns of …

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Read More »